In the midst of central London, a successful Indian restaurant called 'Gaylord' is run by a Londoner of Indian origin called Pinu. A simple soul at heart, Pinu has many complexes - a special one being that he is a virgin and has experienced no intimacy with a woman. To top that, his biggest fear is to be laughed at by people an ever-repeating phenomenon with him. Pinu is quite an introvert and has no real friends... the closest he has ever gotten to a friendship is with his foster brother Rajat, who is quite a contrast to his own personality. Rajat is very fond of Pinu, though is often a source of annoyance to him as he finds Pinu really funny.
One day, a young Indian fellow called Kamlesh come to his restaurant and asks for a job as a stand-up comedian. Quit thrown off, Pinu initially refuses but finally lets him join as a cook, who also does a stand-up act in the evenings. On the same day, he hires a new cashier - Renu, a young art student from India, who has a passion for caricatures. Life changes dramatically for Pinu as Gaylord begins to transforms. Renu works on the look of the place makes cheerful caricatures for customers while Kamlesh is fabulous cook with a great talent for making people laugh in his acts soon the restaurant is more happening and the business is much better. But the greatest difference in Pinu's personality now as he lets himself hang-out a bit with them.
One fine day, Pinu is thrown in to a daze as he walks away from the restaurant, he has discovered a totally new fear he might be Gay! Pinu seeks refuge in Rajat's advice which is quite simply screw a woman! On a mission now, Pinu goes on a rampage seeking available women for a sexual rendezvous. However, it leads to him suffering another string of tragicomic situation, ending up feeling humiliated and laughed at! Straight!! is a funny tale about Pinu, who struggles with himself, his fears and his complexes to come out as straight and find himself a love story.