Phir Ek Sazish is a murder mystery based on a real-life incident that happened in London. Rohan is a casanova who is a typical angry young man albeit with sentiments. His girlfriend's mother is murdered and the girlfriend asks his help to find the killer.
The killer is also after Muskan and her friends but the killer manages to kill Muskaan's friends despite the efforts of Rohan and now Rohan must save Muskaan and get to the serial killer.